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Nephrol Dial Transplant (1995) 10: 230-233
© 1995 European Renal Association-European Dialysis and Transplant Association


research-article

Prevention of hepatitis C infection in haemodialysis units. A prospective study

A. Blumberg1,, C. Zehnder1 and J. J. Burckhardt2

1Division of Nephrology, Department of Medicine, Kantonsspital Aarau Bern, Switzerland 2ZLB, Blutspendedienst SRK Bern, Switzerland

Correspondence and offprint requests to: Correspondence and offprint requests to: Prof A. Blumberg, Nephrologie, Kantonsspital, CH-5001 Aarau, Switzerland.

A prospective study was begun in our haemodialysis unit after four previously negative patients were found to be anti-HCV positive. A dedicated area and dedicated dialysis equipment (but not a separate room) were assigned to anti-HCV-positive patients and testing for HCV antibodies was performed every 3 months. A total of 131 patients were treated during the study period of 18 months. Of these, 50 patients were dialysed during the entire 18 months, and 21 were available to be tested six or more months after having left the centre. During the first 6 weeks after implementing the precautions two more anti-HCV-positive patients were detected. However, during the rest of the study period no further newly infected patients were found. It is concluded that the spread of HCV infection in a haemodialysis environment can be prevented by limited isolation procedures.

Keywords: hepatitis C; anti-HCV antibodies; HCV RNA; haemodialysis


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