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Nephrol Dial Transplant (2002) 17: 21-23
© 2002 European Renal Association-European Dialysis and Transplant Association

IV.3.3 Toxicity of immunosuppression

Guidelines

A. Careful long-term monitoring of graft recipients is mandatory to discover signs of immunosuppressive drug toxicity, in particular nephrotoxicity.

(Evidence level C)

B. In the case of a discrepancy between the drug dose and signs of toxicity, then a thorough pharmacokinetic analysis should be performed.

(Evidence level C)

C. Cardiovascular, renal and metabolic risks and the risk of de novo malignancy must be considered in a long-term monitoring programme.

(Evidence level C)


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