Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (16)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Guerin, A.
Right arrow Articles by Marchais, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Guerin, A.
Right arrow Articles by Marchais, S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Nephrol Dial Transplant (1992) 7: 323-326
© 1992 European Renal Association-European Dialysis and Transplant Association

research-article

Response to vaccination against tetanus in chronic haemodialysed patients

A. Guerin1,, Y. Buisson2, Marie Thérèse Nutini3, P. Saliou3, G. London1 and S. Marchais1

1F.H. ManhÈs, Hospital Center Fleury Mérogis 2Laboratory of Clinical Biology Val de Grâce HIA Paris; 3Pasteur-MÈrieux Marnes la Coquette

Correspondence and offprint requests to: Dr A. Guérin, F.H. Manhés, 91700 Fleury-Mèrogis, France

We studied the response to vaccination against tetanus and the changes in the antibody titers 6 months after this vaccination in 66 haemodialysed patients with chronic renal failure. We also investigated the factors that may affect the quality of this immune response. After the booster injection 96.5% of patients had antitetanus antibody titres considered to be protective (0.06 HU/ml). However, the titre of these antibodies rapidly declined and after 6 months, only 62% of the haemodialysed patients had a titre >0.06 HU/ml. Among the different factors considered, only age significantly impaired or reduced the immune response. In addition, the acquisition of protection against tetanus was independent of the response to vaccination against hepatitis B in the same subjects. This study showed the efficacy and safety of vaccination against tetanus in hemodialysed patients, though the antibody titres should be assayed several months after vaccination to confirm the persistence of immunization.

Keywords: vaccination against tetanus; haemodialysis


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Nephrol Dial TransplantHome page
N. Janus, L.-V. Vacher, S. Karie, E. Ledneva, and G. Deray
Vaccination and chronic kidney disease
Nephrol. Dial. Transplant., March 1, 2008; 23(3): 800 - 807.
[Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.