NDT Advance Access originally published online on September 22, 2004
Nephrology Dialysis Transplantation 2004 19(11):2693-2696; doi:10.1093/ndt/gfh455
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Nephrol Dial Transplant Vol. 19 No. 11 © ERA-EDTA 2004; all rights reserved
Editorial Comment
Type 2 diabetes mellitus in children and adolescentsthe beginning of a renal catastrophe?
Hospital for Children and Adolescents, University of Leipzig, Oststrasse 2125, D-04317 Leipzig, Germany
Correspondence and offprint requests to: Professor Wieland Kiess, MD, Hospital for Children and Adolescents, Oststrasse 2125, D-04317 Leipzig, Germany. Email: kiw@medizin.uni-leipzig.de
Keywords: adolescents; body mass index; children; genetics; lifestyle; obesity; renal failure; type 2 diabetes mellitus
| The first 150 words of the full text of this article appear below. |
| Introduction |
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Changes in food consumption and exercise are fueling a worldwide increase in obesity in children and adolescents. As a consequence of this dramatic development an increasing rate of type 2 diabetes mellitus has been recorded in children and adolescents around the world. Both genetic and environmental factors contribute to the pathogenesis of type 2 diabetes. Preventive programmes fighting obesity in children should be developed on a large scale. It is the prevention of obesity that will help to reverse the emerging epidemic of type 2 diabetes. Preventive programmes should focus on exercise training and reduction of sedatory behaviour such as television viewing, should encourage healthy nutrition and support general education programmes, since lower school education is clearly associated with higher obesity rates and hence susceptibility to acquire type 2 diabetes. Until recently it has been assumed that type 2 diabetes mellitus occurs only rarely at a young age. In the
| Definition and epidemiology |
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| Pathogenesis: genetics and environmental factors |
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| Diagnosis and clinical presentation |
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| Consequences in adult life |
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| Treatment and prevention |
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| Perspectives |
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A. K. Choudhary, L. F. Donnelly, J. M. Racadio, and J. L. Strife Diseases Associated with Childhood Obesity Am. J. Roentgenol., April 1, 2007; 188(4): 1118 - 1130. [Abstract] [Full Text] [PDF] |
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