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NDT Advance Access originally published online on September 22, 2004
Nephrology Dialysis Transplantation 2004 19(11):2693-2696; doi:10.1093/ndt/gfh455
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Nephrol Dial Transplant Vol. 19 No. 11 © ERA-EDTA 2004; all rights reserved


Editorial Comment

Type 2 diabetes mellitus in children and adolescents—the beginning of a renal catastrophe?

Wieland Kiess, Antje Böttner, Susann Blüher, Klemens Raile, Angela Galler and Thomas Michael Kapellen

Hospital for Children and Adolescents, University of Leipzig, Oststrasse 21–25, D-04317 Leipzig, Germany

Correspondence and offprint requests to: Professor Wieland Kiess, MD, Hospital for Children and Adolescents, Oststrasse 21–25, D-04317 Leipzig, Germany. Email: kiw@medizin.uni-leipzig.de

Keywords: adolescents; body mass index; children; genetics; lifestyle; obesity; renal failure; type 2 diabetes mellitus

The first 150 words of the full text of this article appear below.



   Introduction
 
Changes in food consumption and exercise are fueling a worldwide increase in obesity in children and adolescents. As a consequence of this dramatic development an increasing rate of type 2 diabetes mellitus has been recorded in children and adolescents around the world. Both genetic and environmental factors contribute to the pathogenesis of type 2 diabetes. Preventive programmes fighting obesity in children should be developed on a large scale. It is the prevention of obesity that will help to reverse the emerging epidemic of type 2 diabetes. Preventive programmes should focus on exercise training and reduction of sedatory behaviour such as television viewing, should encourage healthy nutrition and support general education programmes, since lower school education is clearly associated with higher obesity rates and hence susceptibility to acquire type 2 diabetes. Until recently it has been assumed that type 2 diabetes mellitus occurs only rarely at a young age. In the . . . [Full Text of this Article]



   Definition and epidemiology
 


   Pathogenesis: genetics and environmental factors
 


   Diagnosis and clinical presentation
 


   Consequences in adult life
 


   Treatment and prevention
 


   Perspectives
 

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[Abstract] [Full Text] [PDF]