Skip Navigation


NDT Advance Access originally published online on May 2, 2008
Nephrology Dialysis Transplantation 2008 23(7):2138-2141; doi:10.1093/ndt/gfn160
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
23/7/2138    most recent
gfn160v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (1)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Mimran, A.
Right arrow Articles by du Cailar, G.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mimran, A.
Right arrow Articles by du Cailar, G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


Dietary sodium: the dark horse amongst cardiovascular and renal risk factors

Albert Mimran and Guilhem du Cailar

Department of Internal Medicine, Hôpital Lapeyronie, Montpellier Cedex, France

Correspondence and offprint requests to: Albert Mimran, Department of Internal Medicine, Hôpital Lapeyronie, 34295 Montpellier Cedex 5, France. Tel: +33-4-67-33-84-43; Fax +33-4-67-33-84-53; E-mail: amimran@wanadoo.fr

Keywords: left ventricular hypertrophy; microalbuminuria; sodium intake; hypertension

The first 150 words of the full text of this article appear below.

In American and European populations, the estimated median values of salt intake are 7 and 10 g/day in women and men, respectively. Whether these amounts of salt are inocuous or deleterious is a subject of large debate between pro [1–4] and con [5] recommendations of a large-scale reduction of sodium intake. In addition to the well-admitted effect of sodium on blood pressure, several clinical and experimental observations are in favour of non-pressure-related effects of salt that could contribute to its influence on cardiovascular outcome.



   Dietary salt and blood pressure
 
In clinical research and practice, measurement of 24-h urinary sodium excretion is probably the most reliable estimate of sodium intake, with a variation coefficient of ~20% [6]. Table salt accounts for ~10%, whereas cooking and food salt represent 5 and 85% of total intake, respectively [7]. The use of the sodium-to-creatinine ratio on a single-spot urine sample, which . . . [Full Text of this Article]



   Non-pressure mediated effects of dietary sodium
 


   Does the effect of dietary sodium on the cardiovascular system translate into an influence on cardiovascular risk in observational studies?
 


   Is sodium reduction associated with reduction in cardiovascular risk in interventional studies?
 


   Putative mechanism (s) involved in the deleterious effect of salt
 


   Conclusion
 

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Nephrol Dial TransplantHome page
N. Lameire, D. C. Wheeler, and J. Floege
Salt wars
Nephrol. Dial. Transplant., September 1, 2008; 23(9): 2715 - 2715.
[Full Text] [PDF]

Home page
 Nephrol Dial TransplantHome page
D. A. McCarron
Dietary sodium and cardiovascular and renal disease risk factors: dark horse or phantom entry?
Nephrol. Dial. Transplant., July 1, 2008; 23(7): 2133 - 2137.
[Full Text] [PDF]